Felix Sahm Selected Research

Nervous System Neoplasms (Neoplasms, Nervous System)

1/2019	Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles.
3/2015	Melanotic tumors of the nervous system are characterized by distinct mutational, chromosomal and epigenomic profiles.

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Felix Sahm Research Topics

Disease

106	Neoplasms (Cancer) 12/2022 - 01/2011
49	Glioma (Gliomas) 12/2022 - 08/2010
36	Glioblastoma (Glioblastoma Multiforme) 06/2022 - 01/2012
23	Meningioma (Meningiomas) 12/2022 - 03/2013
18	Astrocytoma (Pilocytic Astrocytoma) 12/2022 - 02/2011
10	Brain Neoplasms (Brain Tumor) 01/2022 - 02/2015
8	Medulloblastoma 01/2021 - 01/2016
6	Sarcoma (Soft Tissue Sarcoma) 01/2022 - 06/2011
5	Oligodendroglioma 12/2022 - 02/2011
5	Disease Progression 12/2021 - 11/2017
4	Lymphoma (Lymphomas) 01/2022 - 09/2014
4	Carcinogenesis 11/2020 - 10/2011
3	Necrosis 01/2020 - 11/2018
2	Primitive Neuroectodermal Tumors (PNET) 01/2021 - 02/2016
2	Ependymoma 01/2021 - 01/2019
2	Radiation induced meningioma 11/2020 - 01/2017
2	Leukemia 12/2019 - 01/2017
2	Genomic Instability 12/2019 - 01/2019
2	Nervous System Neoplasms (Neoplasms, Nervous System) 01/2019 - 03/2015
2	Hypoxia (Hypoxemia) 11/2015 - 01/2014
1	Acoustic Neuroma (Acoustic Neurinoma) 04/2022
1	Autoimmune Diseases of the Nervous System 01/2022
1	Residual Neoplasm 01/2022
1	Angiomyoma (Angioleiomyoma) 01/2022
1	Fatigue 01/2022

Drug/Important Bio-Agent (IBA)

25	Proteins (Proteins, Gene)FDA Link 12/2022 - 08/2010
18	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2022 - 02/2011
17	Biomarkers (Surrogate Marker)IBA 12/2022 - 07/2011
14	DNA (Deoxyribonucleic Acid)IBA 12/2022 - 03/2013
13	RNA (Ribonucleic Acid)IBA 01/2022 - 01/2017
9	Biological ProductsIBA 01/2022 - 03/2015
9	EnzymesIBA 01/2021 - 10/2011
8	ParaffinIBA 12/2022 - 06/2011
8	Tryptophan (L-Tryptophan)FDA Link 01/2021 - 01/2011
7	Formaldehyde (Formol)FDA Link 12/2022 - 06/2011
7	Pharmaceutical PreparationsIBA 06/2022 - 08/2016
7	Temozolomide (Temodar)FDA LinkGeneric 11/2020 - 06/2013
5	Phosphotransferases (Kinase)IBA 01/2022 - 01/2012
5	MethyltransferasesIBA 01/2021 - 01/2014
5	Bevacizumab (Avastin)FDA Link 11/2020 - 10/2015
4	AntigensIBA 01/2021 - 02/2015
4	KynurenineIBA 01/2021 - 01/2011
4	VaccinesIBA 01/2021 - 08/2014
4	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2021 - 10/2011
4	Messenger RNA (mRNA)IBA 01/2020 - 11/2015
3	ChromatinIBA 01/2021 - 01/2019
3	Telomerase (Telomerase Reverse Transcriptase)IBA 01/2021 - 12/2013
3	MicroRNAs (MicroRNA)IBA 01/2021 - 12/2016
3	Transcription Factors (Transcription Factor)IBA 01/2020 - 01/2015
3	NucleotidesIBA 12/2019 - 01/2016
3	Histones (Histone)IBA 01/2018 - 01/2012
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2022 - 06/2013
2	Peptides (Polypeptides)IBA 01/2022 - 05/2015
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022 - 01/2021
2	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2020
2	capivasertibIBA 01/2022 - 01/2017
2	Reticulin (Reticular Fiber)IBA 01/2022 - 04/2014
2	CollagenIBA 01/2022 - 10/2019
2	CalciumIBA 01/2021 - 01/2019
2	Amino Acids FDA Link 01/2021 - 01/2017
2	ErbB Receptors (EGF Receptor)IBA 01/2021 - 01/2018
2	Protein Subunit VaccinesIBA 01/2021 - 01/2021
2	Histone Deacetylase InhibitorsIBA 01/2021 - 12/2019
2	Codon (Codons)IBA 01/2021 - 01/2017
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2020 - 01/2020
2	Mitogen-Activated Protein KinasesIBA 09/2020 - 01/2018
2	trametinibIBA 09/2020 - 01/2019
2	Essential Amino AcidsIBA 01/2020 - 03/2016
2	NAD (NADH)IBA 01/2020 - 06/2013
2	Lomustine (CCNU)FDA Link 11/2019 - 11/2017
2	Small Interfering RNA (siRNA)IBA 04/2019 - 01/2015
2	APTIBA 01/2019 - 11/2018
2	1,4-dinitro-2-methyl-2-buteneIBA 01/2019 - 12/2016
2	Interleukin-6 (Interleukin 6)IBA 01/2019 - 02/2014
2	Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA 01/2018 - 12/2013
2	VemurafenibIBA 01/2018 - 09/2012
2	EpitopesIBA 01/2017 - 02/2015
2	alpha-hydroxyglutarateIBA 01/2017 - 01/2012
2	GlucocorticoidsIBA 01/2015 - 01/2014
2	Alkylating AgentsIBA 01/2014 - 06/2013
2	Protein Kinases (Protein Kinase)IBA 01/2014 - 09/2013
1	VimentinIBA 12/2022
1	CarbonIBA 01/2022
1	src-Family KinasesIBA 01/2022
1	Dasatinib (BMS 354825)FDA Link 01/2022
1	HLA Antigens (Human Leukocyte Antigens)IBA 01/2022
1	diazoluminolmelaninIBA 01/2022
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2022
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2022

Therapy/Procedure

36	Therapeutics 01/2022 - 08/2010
17	Radiotherapy 04/2022 - 12/2015
12	Drug Therapy (Chemotherapy) 06/2022 - 01/2014
5	Immunotherapy 01/2021 - 02/2015
3	Ligation 02/2015 - 05/2013
2	Salvage Therapy 01/2022 - 01/2019
2	Aftercare (After-Treatment) 01/2021 - 01/2016
2	Chemoradiotherapy 06/2013 - 01/2013
1	Proton Therapy 04/2022
1	Heavy Ion Radiotherapy 01/2022
1	Operative Surgical Procedures 01/2022